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Our Health Library information does not replace the advice of a doctor. Please be advised that this information is made available to assist our patients to learn more about their health. Our providers may not see and/or treat all topics found herein.

Doravirine Oral Tablet (DORAVIRINE - ORAL)

For HIV.

Brand Name(s): Pifeltro

Generic Name: Doravine

Instructions

This medicine may be taken with or without food.

Swallow with a full glass (8 oz) of water unless your doctor gives you different instructions.

Ask your doctor if any of your medicines need to be taken at the same time.

This medicine will work best if you take it at about the same time every day.

Space doses evenly to keep a steady amount of medicine in the body.

Store at room temperature away from heat, light, and moisture. Do not keep in the bathroom.

This medicine does not stop the spread of viruses that are passed through the blood or during sex.

Always use condoms during sex.

Do not share needles or other personal objects such as shavers or toothbrushes.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

If you forget to take a dose on time, take it as soon as you remember. If it is almost time for the next dose, do not take the missed dose. Return to your normal schedule. Do not take 2 doses at one time.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

Use effective birth control to avoid pregnancy.

Keep all appointments for medical exams and tests while on this medicine.

Do not take the medicine more than once during 24 hours.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.

Do not use the medication any more than instructed.

This medicine may cause dizziness or fainting, especially after exercising or in hot weather. Be very careful when standing or sitting up quickly.

If possible, avoid using with marijuana or other medicines that can cause dizziness or drowsiness. These include allergy/cold products, muscle relaxers, sleep aids, and pain relievers.

Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive or operate machinery until you know how this medicine will affect you.

Please check with your doctor before drinking alcohol while on this medicine.

Family should check on the patient often. Call the doctor if patient becomes more depressed, has thoughts of suicide, or shows changes in behavior.

Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding.

It is unknown if this medicine passes into breast milk. Ask your doctor before breastfeeding.

Do not take St. John's wort while on this medicine.

Do not share this medicine with anyone who has not been prescribed this medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • diarrhea
  • dizziness or drowsiness
  • bad dreams
  • headaches
  • nausea
  • stomach upset or abdominal pain

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • changes in memory, mood, or thinking
  • cough that does not go away
  • changes in areas of body fat may alter your body shape
  • fever or chills
  • swelling in the neck or throat
  • numbness or tingling in hands and feet
  • hallucinations (unusual thoughts, seeing or hearing things that are not real)
  • severe or persistent headache
  • fast or irregular heart beats
  • irritability
  • loss of movement anywhere on the body
  • muscle weakness
  • joint or muscle pain
  • nervousness
  • shortness of breath
  • difficulty speaking
  • slurred speech
  • suicidal thoughts
  • difficulty swallowing
  • difficulty adjusting to changes in temperature
  • unusual or unexplained tiredness or weakness
  • unsteadiness while walking
  • unexpected or extreme weight loss

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

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